CD317 (BST2/PDCA-1) Mouse anti-Human, Clone: 26F8, Functional Grade, eBioscience™

Mouse Monoclonal Antibody, Functional Grade

Overview
Brand: Affymetrix eBioscience

Manufacturer Part Number: 16-3179-82

100UG:ANTI-HUMAN CD317(BST2/PDCA-1)FUNCTIONAL

UNSPSC: 12352200

Code: Z2

Additional Details:
Additional Details: Weight: 0.01000kg



Disclaimers: For Research Use Only.

Product Code. 15238607

Quantity Price
1 £ 188.0 / 100µg
Estimated Shipment date
from Supplier 24-02-2017
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Description and Specification

Specification

Antigen CD317 (BST2/PDCA-1)
Format Purified
Formulation aqueous buffer, no sodium azide
Host Species Mouse
Applications Flow Cytometry
Applications Functional Assay
Isotype IgG1
Quantity 100μg
Regulatory Status RUO
Species Reactivity Human
Storage Requirements Store at 2-8°C.
Primary or Secondary Primary
Monoclonal or Polyclonal Monoclonal
Clone 26F8
Concentration 1mg/mL
Conjugate Unlabeled

This 26F8 monoclonal antibody reacts with human CD317 (also known as BST2 and tetherin). CD317 is a 30-36kDa type II transmembrane protein expressed on B cells and bone marrow stromal cells. Although reports have indicated that CD317 mRNA is detectable in activated T cells, protein expression in primary T cells and macrophages is undetectable. Moreover, certain T cell lines, such as Jurkat, do not express detectable levels of CD317 protein. CD317 has been associated with pre-B cell growth and the terminal differentiation of plasma B cells. More recently, this molecule has been reported to prevent HIV-1 virion release from the surface of infected cells, leading to reuptake and degradation of the virus. This activity is inhibited by the HIV-1 accessory protein Vpu. CD317 has been identified as the ligand for the ILT7 receptor.