CD314 (NKG2D) Mouse anti-Human, PE, Clone: 5C6, eBioscience™

Mouse Monoclonal Antibody

Brand: Affymetrix eBioscience

Manufacturer Part Number: 12-5879-41

25TEST Anti-Human CD314 (NKG2D) PE

Code: NEW

Additional Details:
Additional Details: Weight: 0.23750kg

Disclaimers: For Research Use Only.

Product Code. 15587036

Quantity Price
1 £101.60 / 25 tests
Estimated Shipment date
from Supplier 01-11-2016
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Description and Specification


Antigen CD314 (NKG2D)
Applications Flow Cytometry
Clone 5C6
Concentration 5μL (0.25μg)/test
Conjugate PE
Format Conjugated
Formulation aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer
Gene Alias KLRK1
Host Species Mouse
Isotype IgG2a
Quantity 25 tests
Regulatory Status RUO
Species Reactivity Human
Storage Requirements Store at 2-8°C. Do not freeze. Light-sensitive material.
Primary or Secondary Primary
Monoclonal or Polyclonal Monoclonal

The 5C6 monoclonal antibody reacts with the human NKG2D, a 42kDa lectin-like molecule expressed by NK cells, γδ T cells, some CD4+ and CD8+ T cells. Human NKG2D forms complexes with DAP10, a membrane adaptor protein, and has the ability to costimulate multiple NK activation receptors. The counter-receptor for human NKG2D has been identified as MICA/MICB expressed on epithelial tumors from lung, breast, kidney, ovary, prostate and colon carcinoma. 5C6 and 1D11 block binding of soluble MICA to γδ TCR T cell clones and inhibit lysis by these cells. 5C6 and 1D11 induced NKG2D function of redirected lysis of FcReceptor bearing P815 cells.