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CD314 (NKG2D) Mouse anti-Human, FITC, Clone: 1D11, eBioscience™

Mouse Monoclonal Antibody

Brand:  Affymetrix eBioscience 11-5878-42

Code : NEW

Additional Details : Weight : 0.23750kg

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Product Code. 15546576

  • £155.16 / 100 tests


EU Stock 4
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Disclaimers:

For Research Use Only.


Description

Description

The 1D11 monoclonal antibody reacts with the human NKG2D, a 42kDa lectin-like molecule expressed by NK cells, gamma delta T cells, CD8+ T cells, and some CD4+ T cells. Human NKG2D forms complexes with DAP10, a membrane adaptor protein, and has the ability to costimulate multiple NK activation receptors. The counter-receptor for human NKG2D has been identified as MICA/MICB expressed on epithelial tumors from lung, breast, kidney, ovary, prostate and colon carcinoma. 5C6 and 1D11 block binding of soluble MICA to gamma delta TCR T cell clones and inhibit lysis by these cells. 5C6 and 1D11 induced NKG2D function of redirected lysis of FcReceptor bearing P815 cells.
Specifications

Specifications

CD314 (NKG2D)
1D11
FITC
Conjugated
Murine
100 Tests
Store at 2-8°C. Do not freeze. Light-sensitive material.
Monoclonal
Flow Cytometry
5μL (0.125μg)/test
aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer
KLRK1
IgG1
RUO
Primary
Human