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CD31 (PECAM-1) Mouse anti-Human, APC, Clone: WM-59 (WM59), eBioscience™

Mouse Monoclonal Antibody

£71.75 - £154.00

Specifications

Antigen CD31 (PECAM-1)
Clone WM-59 (WM59)
Target Species Human
Conjugate APC
Isotype IgG1, kappa
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Products 2
Product Code Brand Quantity Price Quantity & Availability  
Product Code Brand Quantity Price Quantity & Availability  
15567906 View Documents Affymetrix eBioscience
17-0319-41
25 Tests £71.75
25 tests View alternative products
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Estimated Shipment date
from Supplier 06-04-2020
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15577906 View Documents Affymetrix eBioscience
17-0319-42
100 Tests £154.00
100 tests View alternative products
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EU Stock 11 Please to purchase this item. Need a web account? Register with us today!
Description

Description

CD31 (platelet endothelial cell adhesion molecule-1, PECAM-1) is an inhibitory coreceptor involved in regulation of T cell and B cell signaling by a dual immunoreceptor tyrosine-based inhibitory motif (ITIM) that upon associated kinases-mediated phosphorylation provide docking sites for protein-tyrosine phosphatases. CD31 is expressed ubiquitously within the vascular compartment and is located mainly at junctions between adjacent cells. N-terminal Ig-like domain of CD31 is responsible for its homophilic binding, which plays an important role in cell-cell interactions. CD31 is a multifunctional molecule with diverse roles in modulation of integrin-mediated cell adhesion, transendothelial migration, angiogenesis, apoptosis, negative regulation of immunoreceptor signaling, autoimmunity, macrophage phagocytosis, IgE-mediated anaphylaxis and thrombosis. It is one of key regulatory molecules in vascular system.
Specifications

Specifications

CD31 (PECAM-1)
Human
IgG1, kappa
Monoclonal
Liquid
Antibody
4° C, store in dark, DO NOT FREEZE!
WM-59 (WM59)
APC
Flow Cytometry
Primary
Monoclonal
PBS with 0.1% gelatin, 0.2% BSA and 0.09% sodium azide; pH 7.2
RUO

For Research Use Only.