CD307e (FcRL5) Mouse anti-Human, eFluor 660, Clone: 509F6, eBioscience™

Mouse Monoclonal Antibody

Brand: Affymetrix eBioscience

Manufacturer Part Number: 50-3078-41

25TEST Anti-Human CD307e (FcRL5) eFluor 660

Code: NEW

Additional Details:
Additional Details: Weight: 0.23750kg

Disclaimers: For Research Use Only.

Product Code. 15569926

Quantity Price
1 £120.20 / 25 tests
Estimated Shipment date
from Supplier 28-10-2016
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Description and Specification


Antigen CD307e (FcRL5)
Applications Flow Cytometry
Clone 509F6
Concentration 5μL (1.0μg)/test
Conjugate eFluor 660
Format Conjugated
Formulation aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer
Gene Alias Fc receptor-like 5, IRTA2
Host Species Mouse
Isotype IgG2a
Quantity 25 tests
Regulatory Status RUO
Species Reactivity Human
Storage Requirements Store at 2-8°C. Do not freeze. Light-sensitive material.
Primary or Secondary Primary
Monoclonal or Polyclonal Monoclonal

The 509F6 monoclonal antibody reacts with human CD307e which is also known as Fc receptor-like 5, FcRL5, FcRH5, or IRTA2. CD307e is a surface protein expressed selectively on naïve mature B cells and on bone marrow plasma cells, and binds to all IgG isotypes. CD307e functions as an inhibitory coreceptor on mature B cells in humans via the recruitment of the phosphatase SHP-1 to its two immunoreceptor tyrosine-based inhibitory motifs (ITIM). CD307e can also exist in soluble form and high levels of soluble CD307e have been detected in the blood of patients with multiple myeloma, chronic lymphocytic leukemia, and mantle cell lymphoma. Because surface-bound CD307e is also highly-expressed on malignant B cells from multiple myeloma, chronic lymphocytic leukemia, and mantle cell lymphoma patients, CD307e may be a useful therapeutic target for the treatment of these cancers.