CD303a Mouse anti-Human, PE-Cy7, Clone: 201A, eBioscience™

Mouse Monoclonal Antibody

Overview
Brand: Affymetrix eBioscience

Manufacturer Part Number: 25-9818-42

Code: NEW

Additional Details:
Additional Details: Weight: 0.23750kg



Disclaimers: For Research Use Only.

Product Code. 15538676

Quantity Price
1 £ 217.06 / 100 tests
Estimated Shipment date
from Supplier 03-04-2017
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Description and Specification

Specification

Format Conjugated
Applications Flow Cytometry
Host Species Mouse
Conjugate PE-Cy7
Quantity 100 tests
Regulatory Status RUO
Antigen CD303a
Monoclonal or Polyclonal Monoclonal
Storage Requirements Store at 2-8°C. Do not freeze. Light-sensitive material. This tandem dye is sensitive to photo-induced oxidation. Protect this vial from light during storage
Primary or Secondary Primary
Isotype IgG2a
Species Reactivity Human
Gene Alias BDCA-2, Clec4C
Formulation aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer
Concentration 5μL (0.25μg)/test
Clone 201A

This 201A monoclonal antibody reacts with human CD303a, which is also known as CLEC4C or Blood Dendritic Cell Antigen 2 (BDCA-2). This type II transmembrane protein is expressed almost exclusively on plasmacytoid dendritic cells, which secrete type I interferon during antiviral and antitumor responses. Studies have demonstrated that CD303a binds asialo-galactosyl-oligosaccharides on invading pathogens, resulting in the activation of signaling pathways that lead to CD303a internalization and downregulation of interferon production.