CD303a Mouse anti-Human, FITC, Clone: 201A, eBioscience™

Mouse Monoclonal Antibody

Overview
Brand: Affymetrix eBioscience

Manufacturer Part Number: 11-9818-42

Code: NEW

Additional Details:
Additional Details: Weight: 0.23750kg



Disclaimers: For Research Use Only.

Product Code. 15526636

Quantity Price
1 £ 182.82 / 100 tests
EU Stock 4
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Description and Specification

Specification

Storage Requirements Store at 2-8°C. Do not freeze. Light-sensitive material.
Regulatory Status RUO
Antigen CD303a
Concentration 5μL (0.125μg)/test
Monoclonal or Polyclonal Monoclonal
Species Reactivity Human
Gene Alias BDCA-2, Clec4C
Primary or Secondary Primary
Formulation aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer
Isotype IgG2a
Host Species Mouse
Clone 201A
Format Conjugated
Quantity 100 tests
Conjugate FITC
Applications Flow Cytometry

This 201A monoclonal antibody reacts with human CD303a, which is also known as CLEC4C or Blood Dendritic Cell Antigen 2 (BDCA-2). This type II transmembrane protein is expressed almost exclusively on plasmacytoid dendritic cells, which secrete type I interferon during antiviral and antitumor responses. Studies have demonstrated that CD303a binds asialo-galactosyl-oligosaccharides on invading pathogens, resulting in the activation of signaling pathways that lead to CD303a internalization and downregulation of interferon production.