CD303a Mouse anti-Human, APC, Clone: 201A, eBioscience™

Mouse Monoclonal Antibody

Overview
Brand: Affymetrix eBioscience

Manufacturer Part Number: 17-9818-42

Code: NEW

Additional Details:
Additional Details: Weight: 0.23750kg



Disclaimers: For Research Use Only.

Product Code. 15598256

Quantity Price
1 £ 204.82 / 100 tests
EU Stock 8
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Description and Specification

Specification

Conjugate APC
Isotype IgG2a
Storage Requirements Store at 2-8°C. Do not freeze. Light-sensitive material.
Format Conjugated
Concentration 5μL (0.125μg)/test
Primary or Secondary Primary
Formulation aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer
Host Species Mouse
Clone 201A
Gene Alias BDCA-2, Clec4C
Monoclonal or Polyclonal Monoclonal
Antigen CD303a
Applications Flow Cytometry
Regulatory Status RUO
Quantity 100 tests
Species Reactivity Human

This 201A monoclonal antibody reacts with human CD303a, which is also known as CLEC4C or Blood Dendritic Cell Antigen 2 (BDCA-2). This type II transmembrane protein is expressed almost exclusively on plasmacytoid dendritic cells, which secrete type I interferon during antiviral and antitumor responses. Studies have demonstrated that CD303a binds asialo-galactosyl-oligosaccharides on invading pathogens, resulting in the activation of signaling pathways that lead to CD303a internalization and downregulation of interferon production.