CD303a Mouse anti-Human, APC, Clone: 201A, eBioscience™

Mouse Monoclonal Antibody

Overview
Brand: Affymetrix eBioscience

Manufacturer Part Number: 17-9818-41

Code: NEW

Additional Details:
Additional Details: Weight: 0.23750kg



Disclaimers: For Research Use Only.

Product Code. 15588256

Quantity Price
1 £ 80.1 / 25 tests
Estimated Shipment date
from Supplier 04-05-2017
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Description and Specification

Specification

Monoclonal or Polyclonal Monoclonal
Host Species Mouse
Storage Requirements Store at 2-8°C. Do not freeze. Light-sensitive material.
Clone 201A
Primary or Secondary Primary
Concentration 5μL (0.125μg)/test
Antigen CD303a
Format Conjugated
Gene Alias BDCA-2, Clec4C
Species Reactivity Human
Applications Flow Cytometry
Quantity 25 tests
Formulation aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer
Isotype IgG2a
Conjugate APC
Regulatory Status RUO

This 201A monoclonal antibody reacts with human CD303a, which is also known as CLEC4C or Blood Dendritic Cell Antigen 2 (BDCA-2). This type II transmembrane protein is expressed almost exclusively on plasmacytoid dendritic cells, which secrete type I interferon during antiviral and antitumor responses. Studies have demonstrated that CD303a binds asialo-galactosyl-oligosaccharides on invading pathogens, resulting in the activation of signaling pathways that lead to CD303a internalization and downregulation of interferon production.