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CD301b (MGL2) Rat anti-Mouse, eFluor 660, Clone: 11A10-B7, eBioscience™

Rat Monoclonal Antibody

Brand:  Affymetrix eBioscience 50-3011-82

Code : NEW

Additional Details : Weight : 0.09500kg

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Product Code. 15559926

  • £188.93 / 100µg


Estimated Shipment date
from Supplier 27-11-2017
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Disclaimers:

For Research Use Only.


Description

Description

The monoclonal antibody 11A10-B7 recognizes mouse CD301b. CD301b is also known as macrophage galactose-type C-type lectin 2 (MGL2). CD301b expression is restricted to dermal dendritic cells, connection tissue, and bone marrow derived dendritic cells. Macrophages also express CD301b at low levels. CD301b contains a single carbohydrate recognition domain that recognizes protein antigens that have a galactose and N-acetylgalactosamine (Gal/GalNAc). Gal/GalNAc protein antigens are efficiently internalized through CD301b and presented to antigen specific CD4+ cells via MHC Class II. CD301b+ dendritic cells are believed to play an important role in TH2 priming.
Specifications

Specifications

CD301b (MGL2)
11A10-B7
eFluor™ 660
Conjugated
Rat
100μg
Store at 2-8°C. Do not freeze. Light-sensitive material.
Monoclonal
Flow Cytometry
0.2mg/mL
aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer
Macrophage galactose-type C-type lectins 2
IgG2a
RUO
Primary
Murine