CD301b (MGL2) Rat anti-Mouse, eFluor 660, Clone: 11A10-B7, eBioscience™

Rat Monoclonal Antibody

Overview
Brand: Affymetrix eBioscience

Manufacturer Part Number: 50-3011-82

Code: NEW

Additional Details:
Additional Details: Weight: 0.09500kg



Disclaimers: For Research Use Only.

Product Code. 15559926

Quantity Price
1 £ 188.93 / 100µg
Estimated Shipment date
from Supplier 05-05-2017
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Description and Specification

Specification

Concentration 0.2mg/mL
Monoclonal or Polyclonal Monoclonal
Host Species Rat
Formulation aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer
Primary or Secondary Primary
Gene Alias Macrophage galactose-type C-type lectins 2
Conjugate eFluor 660
Clone 11A10-B7
Isotype IgG2a
Species Reactivity Mouse
Storage Requirements Store at 2-8°C. Do not freeze. Light-sensitive material.
Format Conjugated
Applications Flow Cytometry
Quantity 100μg
Antigen CD301b (MGL2)
Regulatory Status RUO

The monoclonal antibody 11A10-B7 recognizes mouse CD301b. CD301b is also known as macrophage galactose-type C-type lectin 2 (MGL2). CD301b expression is restricted to dermal dendritic cells, connection tissue, and bone marrow derived dendritic cells. Macrophages also express CD301b at low levels. CD301b contains a single carbohydrate recognition domain that recognizes protein antigens that have a galactose and N-acetylgalactosamine (Gal/GalNAc). Gal/GalNAc protein antigens are efficiently internalized through CD301b and presented to antigen specific CD4+ cells via MHC Class II. CD301b+ dendritic cells are believed to play an important role in TH2 priming.