CD301b (MGL2), clone: 11A10-B7, eBioscience™
Rat Monoclonal Antibody
Brand: Affymetrix eBioscience 14-3011-82
Code : NEW
Additional Details : Weight : 0.09500kg
DescriptionDescription: The monoclonal antibody 11A10-B7 recognizes mouse CD301b. CD301b is also known as macrophage galactose-type C-type lectin 2 (MGL2). CD301b expression is restricted to dermal dendritic cells, connection tissue, and bone marrow derived dendritic cells. Macrophages also express CD301b at low levels. CD301b contains a single carbohydrate recognition domain that recognizes protein antigens that have a galactose and N-acetylgalactosamine (Gal/GalNAc). Gal/GalNAc protein antigens are efficiently internalized through CD301b and presented to antigen specific CD4+ cells via MHC Class II. CD301b+ dendritic cells are believed to play an important role in TH2 priming.Applications Reported: This 11A10-B7 antibody has been reported for use in immunohistochemical staining of frozen tissue sections, and microscopy.Applications Tested: This 11A10-B7 antibody has been tested by immunohistochemistry of frozen mouse tissue and can be used at less than or equal to 10 μg/mL. It is recommended that the antibody be carefully titrated for optimal performance in the assay of interest.Purity: Greater than 90%, as determined by SDS-PAGE.Aggregation: Less than 10%, as determined by HPLC.Filtration: 0.2μm post-manufacturing filtered.
|PBS with 0.09% sodium azide; pH 7.2|
|IgG2a, lambda, lambda|
|Store at 2-8°C.|
|Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Frozen)|
|Macrophage galactose-type C-type lectins 2, MGL2, Macrophage galactose-type C-type lectin, CD301|
For Research Use Only.