CD301b (MGL2) Rat anti-Mouse, Clone: 11A10-B7, eBioscience™

Rat Monoclonal Antibody

Overview
Brand: Affymetrix eBioscience

Manufacturer Part Number: 14-3011-82

Code: NEW

Additional Details:
Additional Details: Weight: 0.09500kg



Disclaimers: For Research Use Only.

Product Code. 15597436

Quantity Price
1 £ 155.16 / 100µg
Estimated Shipment date
from Supplier 04-05-2017
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Description and Specification

Specification

Monoclonal or Polyclonal Monoclonal
Applications Immunohistochemistry (Frozen)
Applications Microscopy
Host Species Rat
Quantity 100μg
Antigen CD301b (MGL2)
Format Purified
Regulatory Status RUO
Primary or Secondary Primary
Isotype IgG2a
Storage Requirements Store at 2-8°C.
Clone 11A10-B7
Conjugate Unlabeled
Concentration 0.5mg/mL
Species Reactivity Mouse
Formulation aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer
Gene Alias Macrophage galactose-type C-type lectins 2

The monoclonal antibody 11A10-B7 recognizes mouse CD301b. CD301b is also known as macrophage galactose-type C-type lectin 2 (MGL2). CD301b expression is restricted to dermal dendritic cells, connection tissue, and bone marrow derived dendritic cells. Macrophages also express CD301b at low levels. CD301b contains a single carbohydrate recognition domain that recognizes protein antigens that have a galactose and N-acetylgalactosamine (Gal/GalNAc). Gal/GalNAc protein antigens are efficiently internalized through CD301b and presented to antigen specific CD4+ cells via MHC Class II. CD301b+ dendritic cells are believed to play an important role in TH2 priming.