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CD301b (MGL2) Rat anti-Mouse, Clone: 11A10-B7, eBioscience™
Rat Monoclonal Antibody
Brand: Affymetrix eBioscience 14-3011-80
Code : NEW
Additional Details : Weight : 0.09500kg
Description
Description: The monoclonal antibody 11A10-B7 recognizes mouse CD301b. CD301b is also known as macrophage galactose-type C-type lectin 2 (MGL2). CD301b expression is restricted to dermal dendritic cells, connection tissue, and bone marrow derived dendritic cells. Macrophages also express CD301b at low levels. CD301b contains a single carbohydrate recognition domain that recognizes protein antigens that have a galactose and N-acetylgalactosamine (Gal/GalNAc). Gal/GalNAc protein antigens are efficiently internalized through CD301b and presented to antigen specific CD4+ cells via MHC Class II. CD301b+ dendritic cells are believed to play an important role in TH2 priming. Applications Reported: This 11A10-B7 antibody has been reported for use in immunohistochemical staining of frozen tissue sections, and microscopy. Applications Tested: This 11A10-B7 antibody has been tested by immunohistochemistry of frozen mouse tissue and can be used at less than or equal to 10 μg/mL. It is recommended that the antibody be carefully titrated for optimal performance in the assay of interest. Purity: Greater than 90%, as determined by SDS-PAGE. Aggregation: Less than 10%, as determined by HPLC. Filtration: 0.2 μm post-manufacturing filtered.
CD301b is also known as macrophage galactose-type C-type lectin 2 (MGL2). CD301b expression is restricted to dermal dendritic cells, connection tissue, and bone marrow derived dendritic cells. Macrophages also express CD301b at low levels. CD301b contains a single carbohydrate recognition domain that recognizes protein antigens that have a galactose and N-acetylgalactosamine (Gal/GalNAc). Gal/GalNAc protein antigens are efficiently internalized through CD301b and presented to antigen specific CD4+ cells via MHC Class II. CD301b+ dendritic cells are believed to play an important role in TH2 priming.Specifications
CD301b (MGL2) | |
Monoclonal | |
0.5 mg/mL | |
PBS with 0.09% sodium azide; pH 7.2 | |
Macrophage galactose-type C-type lectins 2; MGL2; Macrophage galactose-type C-type lectin; CD301 | |
Rat | |
25 μg | |
Primary | |
Mouse | |
Antibody | |
IgG2a λ |
Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Frozen) | |
11A10-B7 | |
Unconjugated | |
Mgl2 | |
Mgl2 | |
Affinity chromatography | |
RUO | |
216864 | |
4° C | |
Liquid |
For Research Use Only.