CD3 Mouse anti-Rat, PE, Clone: eBioG4.18 (G4.18), eBioscience™

Mouse Monoclonal Antibody

Overview
Brand: Affymetrix eBioscience

Manufacturer Part Number: 12-0030-81

UNSPSC: 12352200

Code: Z2

Additional Details:
Additional Details: Weight: 0.25000kg



Disclaimers: For Research Use Only.

Product Code. 15208419

Quantity Price
1 £ 54.13 / 50µg
Estimated Shipment date
from Supplier 04-05-2017
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Description and Specification

Specification

Host Species Murine
Conjugate PE
Applications Flow Cytometry
Monoclonal or Polyclonal Monoclonal
Clone eBioG4.18 (G4.18)
Gene Alias T3
Regulatory Status RUO
Isotype IgG3
Format Conjugated
Antigen CD3
Primary or Secondary Primary
Quantity 50μg
Formulation aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer
Species Reactivity Rat
Storage Requirements Store at 2-8°C. Do not freeze. Light-sensitive material.
Concentration 0.2mg/mL

The eBioG4.18 monoclonal antibody recognizes the rat CD3 protein. CD3 is a critical component of the T-cell receptor (TCR) and is a marker of the T-cell lineage. CD3 is a complex of several subunits and, upon binding of a TCR ligand, participates in transduction of signals from the TCR to the nucleus which results in a variety of cellular responses including transcription of IL-2 and clonal expansion. in vitro, immobilized G4.18 monoclonal antibody has been demonstrated to activate T cells, while soluble G4.18 inhibited allogeneic mixed-lymphocyte proliferative responses and cell-mediated cytotoxicity to allogeneic target cells. in vivo, G4.18 was demonstrated to induce long-term specific tolerance to an organ allograft.