CD3 Mouse anti-Rat, FITC, Clone: eBioG4.18 (G4.18), eBioscience™

Mouse Monoclonal Antibody

Overview
Brand: Affymetrix eBioscience

Manufacturer Part Number: 11-0030-81

50UG ANTI-RAT CD3 FITC

UNSPSC: 12352200

Code: Z2

Additional Details:
Additional Details: Weight: 0.25000kg



Disclaimers: For Research Use Only.

Product Code. 15227979

Quantity Price
1 £ 42.77 / 50µg
Estimated Shipment date
from Supplier 28-03-2017
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Description and Specification

Specification

Antigen CD3
Formulation aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer
Host Species Mouse
Isotype IgG3
Regulatory Status RUO
Species Reactivity Rat
Primary or Secondary Primary
Monoclonal or Polyclonal Monoclonal
Format Conjugated
Gene Alias T3
Applications Flow Cytometry
Quantity 50μg
Storage Requirements Store at 2-8°C. Do not freeze. Light-sensitive material.
Clone eBioG4.18 (G4.18)
Concentration 0.5mg/mL
Conjugate FITC

The eBioG4.18 monoclonal antibody recognizes the rat CD3 protein. CD3 is a critical component of the T-cell receptor (TCR) and is a marker of the T-cell lineage. CD3 is a complex of several subunits and, upon binding of a TCR ligand, participates in transduction of signals from the TCR to the nucleus which results in a variety of cellular responses including transcription of IL-2 and clonal expansion. in vitro, immobilized G4.18 monoclonal antibody has been demonstrated to activate T cells, while soluble G4.18 inhibited allogeneic mixed-lymphocyte proliferative responses and cell-mediated cytotoxicity to allogeneic target cells. in vivo, G4.18 was demonstrated to induce long-term specific tolerance to an organ allograft.