CD3 Mouse anti-Rat, Clone: eBioG4.18 (G4.18), eBioscience™

Mouse Monoclonal Antibody

Overview
Brand: Affymetrix eBioscience

Manufacturer Part Number: 14-0030-81

Code: NEW

Additional Details:
Additional Details: Weight: 0.09500kg



Disclaimers: For Research Use Only.

Product Code. 15587406

Quantity Price
1 £ 36.08 / 50µg
Estimated Shipment date
from Supplier 03-04-2017
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Description and Specification

Specification

Species Reactivity Rat
Isotype IgG3
Applications Flow Cytometry
Applications Immunohistochemistry
Applications Immunoprecipitation
Applications Western Blotting
Storage Requirements Store at 2-8°C.
Clone eBioG4.18 (G4.18)
Gene Alias T3
Formulation aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer
Monoclonal or Polyclonal Monoclonal
Quantity 50μg
Regulatory Status RUO
Conjugate Unlabeled
Primary or Secondary Primary
Host Species Mouse
Concentration 0.5mg/mL
Antigen CD3
Format Purified

The eBioG4.18 monoclonal antibody recognizes the rat CD3 protein. CD3 is a critical component of the T-cell receptor (TCR) and is a marker of the T-cell lineage. CD3 is a complex of several subunits and, upon binding of a TCR ligand, participates in transduction of signals from the TCR to the nucleus which results in a variety of cellular responses including transcription of IL-2 and clonal expansion. in vitro, immobilized G4.18 monoclonal antibody has been demonstrated to activate T cells, while soluble G4.18 inhibited allogeneic mixed-lymphocyte proliferative responses and cell-mediated cytotoxicity to allogeneic target cells. in vivo, G4.18 was demonstrated to induce long-term specific tolerance to an organ allograft.