CD3 Mouse anti-Rat, Clone: eBioG4.18 (G4.18), eBioscience™

Mouse Monoclonal Antibody

Overview
Brand: Affymetrix eBioscience

Manufacturer Part Number: 14-0030-85

Code: NEW

Additional Details:
Additional Details: Weight: 0.09500kg



Disclaimers: For Research Use Only.

Product Code. 15597406

Quantity Price
1 £ 133.91 / 500µg
EU Stock 6
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Description and Specification

Specification

Applications Flow Cytometry
Applications Immunohistochemistry
Applications Immunoprecipitation
Applications Western Blot
Host Species Murine
Antigen CD3
Conjugate Unlabeled
Format Purified
Isotype IgG3
Quantity 500μg
Primary or Secondary Primary
Regulatory Status RUO
Concentration 0.5mg/mL
Storage Requirements Store at 2-8°C.
Gene Alias T3
Formulation aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer
Clone eBioG4.18 (G4.18)
Species Reactivity Rat
Monoclonal or Polyclonal Monoclonal

The eBioG4.18 monoclonal antibody recognizes the rat CD3 protein. CD3 is a critical component of the T-cell receptor (TCR) and is a marker of the T-cell lineage. CD3 is a complex of several subunits and, upon binding of a TCR ligand, participates in transduction of signals from the TCR to the nucleus which results in a variety of cellular responses including transcription of IL-2 and clonal expansion. in vitro, immobilized G4.18 monoclonal antibody has been demonstrated to activate T cells, while soluble G4.18 inhibited allogeneic mixed-lymphocyte proliferative responses and cell-mediated cytotoxicity to allogeneic target cells. in vivo, G4.18 was demonstrated to induce long-term specific tolerance to an organ allograft.