missing translation for 'onlineSavingsMsg'
Learn More

CD3, clone: eBioG4.18 (G4.18), eBioscience™

Mouse Monoclonal Antibody

Brand:  Affymetrix eBioscience 14-0030-85

Code : NEW

Additional Details : Weight : 0.09500kg

 View more versions of this product

Product Code. 15597406

  • £138.41 / 500µg


EU Stock 1
Add to basket

Description

Description

Description: The eBioG4.18 monoclonal antibody recognizes the rat CD3 protein. CD3 is a critical component of the T-cell receptor (TCR) and is a marker of the T-cell lineage. CD3 is a complex of several subunits and, upon binding of a TCR ligand, participates in transduction of signals from the TCR to the nucleus which results in a variety of cellular responses including transcription of IL-2 and clonal expansion. in vitro, immobilized G4.18 monoclonal antibody has been demonstrated to activate T cells, while soluble G4.18 inhibited allogeneic mixed-lymphocyte proliferative responses and cell-mediated cytotoxicity to allogeneic target cells. in vivo, G4.18 was demonstrated to induce long-term specific tolerance to an organ allograft.Applications Reported: This eBioG4.18 (G4.18) antibody has been reported for use in flow cytometric analysis, immunoprecipitation, immunoblotting (WB), and immunohistochemical staining.Applications Tested: This eBioG4.18 (G4.18) antibody has been tested by flow cytometric analysis of rat splenocytes. This can be used at less than or equal to 0.5 μg per test. A test is defined as the amount (μg) of antibody that will stain a cell sample in a final volume of 100 μL. Cell number should be determined empirically but can range from 10^5 to 10^8 cells/test. It is recommended that the antibody be carefully titrated for optimal performance in the assay of interest.Purity: Greater than 90%, as determined by SDS-PAGE.Aggregation: Less than 10%, as determined by HPLC.Filtration: 0.2μm post-manufacturing filtered.
Specifications

Specifications

CD3
Monoclonal
0.5mg/mL
PBS with 0.09% sodium azide; pH 7.2
P19377, Q64159
FLJ18683, T3E, TCRE
Murine
Affinity chromatography
RUO
Antibody
Monoclonal
Rat
Flow CytometryþImmunohistochemistryþImmunoprecipitationþWestern Blot
eBioG4.18 (G4.18)
Unconjugated
Cd3g
Purified
Cd3d, Cd3g
IgG3, kappa
500μg
Store at 2-8°C.
Primary
25710, 300678
Videos

For Research Use Only.