CD3 Mouse anti-Rat, Clone: eBioG4.18 (G4.18), eBioscience™

Mouse Monoclonal Antibody

Overview
Brand: Affymetrix eBioscience

Manufacturer Part Number: 14-0030-85

500UG Anti-Rat CD3 Purified

Code: NEW

Additional Details:
Additional Details: Weight: 0.09500kg



Disclaimers: For Research Use Only.

Product Code. 15597406

Quantity Price
1 £ 204.0 / 500µg
Estimated Shipment date
from Supplier 23-01-2017
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Description and Specification

Specification

Antigen CD3
Applications Flow Cytometry
Applications Immunohistochemistry
Applications Immunoprecipitation
Applications Western Blotting
Clone eBioG4.18 (G4.18)
Concentration 0.5mg/mL
Conjugate Unlabeled
Format Purified
Formulation aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer
Gene Alias T3
Host Species Mouse
Isotype IgG3
Quantity 500μg
Regulatory Status RUO
Species Reactivity Rat
Storage Requirements Store at 2-8°C.
Primary or Secondary Primary
Monoclonal or Polyclonal Monoclonal

The eBioG4.18 monoclonal antibody recognizes the rat CD3 protein. CD3 is a critical component of the T-cell receptor (TCR) and is a marker of the T-cell lineage. CD3 is a complex of several subunits and, upon binding of a TCR ligand, participates in transduction of signals from the TCR to the nucleus which results in a variety of cellular responses including transcription of IL-2 and clonal expansion. in vitro, immobilized G4.18 monoclonal antibody has been demonstrated to activate T cells, while soluble G4.18 inhibited allogeneic mixed-lymphocyte proliferative responses and cell-mediated cytotoxicity to allogeneic target cells. in vivo, G4.18 was demonstrated to induce long-term specific tolerance to an organ allograft.