CD3 Mouse anti-Rat, Clone: eBioG4.18 (G4.18), eBioscience™

Mouse Monoclonal Antibody

Overview
Brand: Affymetrix eBioscience

Manufacturer Part Number: 14-0030-82

14-0030-82 Affinity Purified anti-rat CD3,Appl.:F,WB,IP,IHC, Size: 100µg

Code: NEW

Additional Details:
Additional Details: Weight: 0.99000kg



Disclaimers: For Research Use Only.

Product Code. 10453940

Quantity Price
1 £ 60.53 / Each
Estimated Shipment date
from Supplier 27-02-2017
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Description and Specification

Specification

Antigen CD3
Format Purified
Formulation aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer
Gene Alias T3
Host Species Mouse
Applications Flow Cytometry
Applications Immunohistochemistry
Applications Immunoprecipitation
Applications Western Blotting
Isotype IgG3
Quantity 100μg
Regulatory Status RUO
Species Reactivity Rat
Storage Requirements Store at 2-8°C.
Primary or Secondary Primary
Monoclonal or Polyclonal Monoclonal
Clone eBioG4.18 (G4.18)
Concentration 0.5mg/mL
Conjugate Unlabeled

The eBioG4.18 monoclonal antibody recognizes the rat CD3 protein. CD3 is a critical component of the T-cell receptor (TCR) and is a marker of the T-cell lineage. CD3 is a complex of several subunits and, upon binding of a TCR ligand, participates in transduction of signals from the TCR to the nucleus which results in a variety of cellular responses including transcription of IL-2 and clonal expansion. in vitro, immobilized G4.18 monoclonal antibody has been demonstrated to activate T cells, while soluble G4.18 inhibited allogeneic mixed-lymphocyte proliferative responses and cell-mediated cytotoxicity to allogeneic target cells. in vivo, G4.18 was demonstrated to induce long-term specific tolerance to an organ allograft.