CD3 Mouse anti-Rat, Biotin, Clone: eBioG4.18 (G4.18), eBioscience™

Mouse Monoclonal Antibody

Overview
Brand: Affymetrix eBioscience

Manufacturer Part Number: 13-0030-85

UNSPSC: 12352200

Code: Z2

Additional Details:
Additional Details: Weight: 0.25000kg



Disclaimers: For Research Use Only.

Product Code. 15219399

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Description and Specification

Specification

Storage Requirements Store at 2-8°C. Do not freeze.
Clone eBioG4.18 (G4.18)
Species Reactivity Rat
Isotype IgG3
Applications Flow Cytometry
Applications Immunohistochemistry
Applications Immunohistochemistry (Frozen)
Regulatory Status RUO
Primary or Secondary Primary
Format Conjugated
Monoclonal or Polyclonal Monoclonal
Host Species Mouse
Antigen CD3
Concentration 0.5mg/mL
Conjugate Biotin
Formulation aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer
Quantity 500μg
Gene Alias T3

The eBioG4.18 monoclonal antibody recognizes the rat CD3 protein. CD3 is a critical component of the T-cell receptor (TCR) and is a marker of the T-cell lineage. CD3 is a complex of several subunits and, upon binding of a TCR ligand, participates in transduction of signals from the TCR to the nucleus which results in a variety of cellular responses including transcription of IL-2 and clonal expansion. in vitro, immobilized G4.18 monoclonal antibody has been demonstrated to activate T cells, while soluble G4.18 inhibited allogeneic mixed-lymphocyte proliferative responses and cell-mediated cytotoxicity to allogeneic target cells. in vivo, G4.18 was demonstrated to induce long-term specific tolerance to an organ allograft.