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CD3 Mouse anti-Rat, Biotin, Clone: eBioG4.18 (G4.18), eBioscience™

Mouse Monoclonal Antibody

Brand:  Affymetrix eBioscience 13-0030-82

UNSPSC : 12352200

Code : Z2

Additional Details : Weight : 0.25000kg

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Product Code. 15209399

  • £78.88 / 100µg


Estimated Shipment date
from Supplier 04-09-2017
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Disclaimers:

For Research Use Only.


Specifications

Description

The eBioG4.18 monoclonal antibody recognizes the rat CD3 protein. CD3 is a critical component of the T-cell receptor (TCR) and is a marker of the T-cell lineage. CD3 is a complex of several subunits and, upon binding of a TCR ligand, participates in transduction of signals from the TCR to the nucleus which results in a variety of cellular responses including transcription of IL-2 and clonal expansion. in vitro, immobilized G4.18 monoclonal antibody has been demonstrated to activate T cells, while soluble G4.18 inhibited allogeneic mixed-lymphocyte proliferative responses and cell-mediated cytotoxicity to allogeneic target cells. in vivo, G4.18 was demonstrated to induce long-term specific tolerance to an organ allograft.
Description & Specifications

Specifications

CD3
eBioG4.18 (G4.18)
Biotin
Conjugated
Murine
100μg
Store at 2-8°C. Do not freeze.
Monoclonal
Immunohistochemistry (Frozen)
0.5mg/mL
aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer
T3
IgG3
RUO
Primary
Rat