CD3 Mouse anti-Human, FITC, Clone: UCHT1, eBioscience™

Mouse Monoclonal Antibody

Overview
Brand: Affymetrix eBioscience

Manufacturer Part Number: 11-0038-80

UNSPSC: 12352200

Code: Z2

Additional Details:
Additional Details: Weight: 0.25000kg



Disclaimers: For Research Use Only.

Product Code. 15227989

Quantity Price
1 £ 72.77 / 25µg
Estimated Shipment date
from Supplier 04-04-2017
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Description and Specification

Specification

Applications Flow Cytometry
Host Species Mouse
Monoclonal or Polyclonal Monoclonal
Conjugate FITC
Isotype IgG1
Storage Requirements Store at 2-8°C. Do not freeze. Light-sensitive material.
Clone UCHT1
Antigen CD3
Gene Alias Leu-4, T3
Format Conjugated
Concentration 0.5mg/mL; 5μL (1μg)/test
Quantity 25μg
Formulation aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer
Species Reactivity Human
Primary or Secondary Primary
Regulatory Status RUO

The UCHT1 monoclonal antibody reacts with human CD3e, a 20kDa subunit of the TCR complex. Along with the other CD3 subunits gamma and delta, the epsilon chain is required for proper assembly, trafficking and surface expression of the TCR complex. CD3 is expressed by thymocytes in a developmentally regulated manner and by all mature T cells. Crosslinking of TCR via immobilized UCHT1 initiates an intracellular biochemical pathway resulting in cellular activation and proliferation.