CD3 Mouse anti-Human, FITC, Clone: HIT3a, eBioscience™

Mouse Monoclonal Antibody

Overview
Brand: Affymetrix eBioscience

Manufacturer Part Number: 11-0039-42

Code: NEW

Additional Details:
Additional Details: Weight: 0.23750kg



Disclaimers: For Research Use Only.

Product Code. 15566306

Quantity Price
1 £ 115.56 / 100 tests
EU Stock 4
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Description and Specification

Specification

Formulation aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer
Isotype IgG2a
Clone HIT3a
Regulatory Status RUO
Primary or Secondary Primary
Storage Requirements Store at 2-8°C. Do not freeze. Light-sensitive material.
Concentration 5μL (1μg)/test
Gene Alias Leu-4, T3
Conjugate FITC
Format Conjugated
Quantity 100 tests
Applications Flow Cytometry
Antigen CD3
Host Species Mouse
Species Reactivity Human
Monoclonal or Polyclonal Monoclonal

The HIT3a monoclonal antibody reacts with human CD3e, a 20kDa subunit of the TCR complex. Along with the other CD3 subunits γ and δ, the ε chain is required for proper assembly, trafficking and surface expression of the TCR complex. CD3 is expressed by thymocytes in a developmentally regulated manner and by all mature T cells. Crosslinking of TCR with HIT3a initiates an intracellular biochemical pathway resulting in cellular activation and proliferation.