CD3 Mouse anti-Human, eVolve 655, Clone: OKT3, eBioscience™

Mouse Monoclonal Antibody

Overview
Brand: Affymetrix eBioscience

Manufacturer Part Number: 86-0037-41

Code: NEW

Additional Details:
Additional Details: Weight: 0.23750kg



Disclaimers: For Research Use Only.

Product Code. 15590817

Quantity Price
1 £ 88.66 / 25 tests
Estimated Shipment date
from Supplier 10-05-2017
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Description and Specification

Specification

Isotype IgG2a
Format Conjugated
Primary or Secondary Primary
Formulation aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer
Conjugate eVolve 655
Applications Flow Cytometry
Quantity 25 tests
Antigen CD3
Monoclonal or Polyclonal Monoclonal
Concentration 5μL
Gene Alias Leu-4, T3
Storage Requirements Store at 2-8°C. Do not freeze. Light-sensitive material. This product should be used within 6 months from the date of receipt.
Species Reactivity Human
Host Species Mouse
Clone OKT3
Regulatory Status RUO

The OKT3 monoclonal antibody reacts with an epitope on the epsilon-subunit within the human CD3 complex. The OKT3 antibody has been reported to have potent immunosuppressive properties in vivo and has been proven effective in the treatment of renal, heart and liver allograft rejection. The CD3 subunits, gamma, delta, and epsilon chains, are required for proper assembly, trafficking and surface expression of the TCR complex. CD3 is expressed by thymocytes in a developmentally regulated manner and by all mature T cells. Crosslinking of TCR initiates an intracellular biochemical pathway resulting in cellular activation and proliferation.