CD3 Mouse anti-Human, eVolve 605, Clone: OKT3, eBioscience™

Mouse Monoclonal Antibody

Overview
Brand: Affymetrix eBioscience

Manufacturer Part Number: 83-0037-41

Code: NEW

Additional Details:
Additional Details: Weight: 0.23750kg



Disclaimers: For Research Use Only.

Product Code. 15520737

Quantity Price
1 £ 88.66 / 25 tests
Estimated Shipment date
from Supplier 09-05-2017
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Description and Specification

Specification

Isotype IgG2a
Storage Requirements Store at 2-8°C. Do not freeze. Light-sensitive material. This product should be used within 6 months from the date of receipt.
Clone OKT3
Regulatory Status RUO
Antigen CD3
Quantity 25 tests
Monoclonal or Polyclonal Monoclonal
Formulation aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer
Primary or Secondary Primary
Host Species Mouse
Format Conjugated
Concentration 5μL
Species Reactivity Human
Gene Alias Leu-4, T3
Applications Flow Cytometry
Conjugate eVolve 605

The OKT3 monoclonal antibody reacts with an epitope on the epsilon-subunit within the human CD3 complex. The OKT3 antibody has been reported to have potent immunosuppressive properties in vivo and has been proven effective in the treatment of renal, heart and liver allograft rejection. The CD3 subunits, gamma, delta, and epsilon chains, are required for proper assembly, trafficking and surface expression of the TCR complex. CD3 is expressed by thymocytes in a developmentally regulated manner and by all mature T cells. Crosslinking of TCR initiates an intracellular biochemical pathway resulting in cellular activation and proliferation.