CD3 Mouse anti-Human, eFluor 450, Clone: UCHT1, eBioscience™

Mouse Monoclonal Antibody

Overview
Brand: Affymetrix eBioscience

Manufacturer Part Number: 48-0038-42

Code: NEW

Additional Details:
Additional Details: Weight: 0.23750kg



Disclaimers: For Research Use Only.

Product Code. 15579616

Quantity Price
1 £ 152.25 / 100 tests
EU Stock 14
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Description and Specification

Specification

Regulatory Status RUO
Antigen CD3
Storage Requirements Store at 2-8°C. Do not freeze. Light-sensitive material.
Monoclonal or Polyclonal Monoclonal
Conjugate eFluor 450
Host Species Mouse
Species Reactivity Human
Applications Flow Cytometry
Isotype IgG1
Quantity 100 tests
Format Conjugated
Primary or Secondary Primary
Clone UCHT1
Gene Alias Leu-4, T3
Concentration 5μL (0.5μg)/test
Formulation aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer

The UCHT1 monoclonal antibody reacts with human CD3e, a 20kDa subunit of the TCR complex. Along with the other CD3 subunits gamma and delta, the epsilon chain is required for proper assembly, trafficking and surface expression of the TCR complex. CD3 is expressed by thymocytes in a developmentally regulated manner and by all mature T cells. Crosslinking of TCR via immobilized UCHT1 initiates an intracellular biochemical pathway resulting in cellular activation and proliferation.