CD3 Mouse anti-Human, Clone: UCHT1, Functional Grade, eBioscience™

Mouse Monoclonal Antibody

Overview
Brand: Affymetrix eBioscience

Manufacturer Part Number: 16-0038-85

UNSPSC: 12352200

Code: Z2

Additional Details:
Additional Details: Weight: 0.00250kg



Disclaimers: For Research Use Only.

Product Code. 15263713

Quantity Price
1 £ 201.16 / 500µg
EU Stock 11
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Description and Specification

Specification

Applications Flow Cytometry
Applications Functional Assay
Quantity 500μg
Regulatory Status RUO
Isotype IgG1
Storage Requirements Store at 2-8°C.
Gene Alias Leu-4, T3
Species Reactivity Human
Clone UCHT1
Primary or Secondary Primary
Format Purified
Host Species Mouse
Conjugate Unlabeled
Antigen CD3
Monoclonal or Polyclonal Monoclonal
Formulation aqueous buffer, no sodium azide

The UCHT1 monoclonal antibody reacts with human CD3e, a 20kDa subunit of the TCR complex. Along with the other CD3 subunits gamma and delta, the epsilon chain is required for proper assembly, trafficking and surface expression of the TCR complex. CD3 is expressed by thymocytes in a developmentally regulated manner and by all mature T cells. Crosslinking of TCR via immobilized UCHT1 initiates an intracellular biochemical pathway resulting in cellular activation and proliferation.