CD3 Mouse anti-Human, Clone: UCHT1, Functional Grade, eBioscience™

Mouse Monoclonal Antibody

Overview
Brand: Affymetrix eBioscience

Manufacturer Part Number: 16-0038-81

UNSPSC: 12352200

Code: Z2

Additional Details:
Additional Details: Weight: 0.01000kg



Disclaimers: For Research Use Only.

Product Code. 15298347

Quantity Price
1 £ 66.65 / 50µg
Estimated Shipment date
from Supplier 04-05-2017
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Description and Specification

Specification

Host Species Murine
Regulatory Status RUO
Primary or Secondary Primary
Isotype IgG1
Applications Flow Cytometry
Applications Functional Assay
Format Purified
Quantity 50μg
Monoclonal or Polyclonal Monoclonal
Antigen CD3
Formulation aqueous buffer, no sodium azide
Conjugate Unlabeled
Clone UCHT1
Storage Requirements Store at 2-8°C.
Species Reactivity Human
Gene Alias Leu-4, T3

The UCHT1 monoclonal antibody reacts with human CD3e, a 20kDa subunit of the TCR complex. Along with the other CD3 subunits gamma and delta, the epsilon chain is required for proper assembly, trafficking and surface expression of the TCR complex. CD3 is expressed by thymocytes in a developmentally regulated manner and by all mature T cells. Crosslinking of TCR via immobilized UCHT1 initiates an intracellular biochemical pathway resulting in cellular activation and proliferation.