CD3 Mouse anti-Human, Clone: SK7, Functional Grade, eBioscience™

Mouse Monoclonal Antibody

Overview
Brand: Affymetrix eBioscience

Manufacturer Part Number: 16-0036-85

500UG:ANTI-HUMAN CD3 FUNCTIONAL GRADE PURIFIED

UNSPSC: 12352200

Code: Z2

Additional Details:
Additional Details: Weight: 0.01000kg



Disclaimers: For Research Use Only.

Product Code. 15278347

Quantity Price
1 £ 232.0 / 500µg
Estimated Shipment date
from Supplier 13-12-2016
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Description and Specification

Specification

Antigen CD3
Applications Flow Cytometry
Applications Functional Assay
Clone SK7
Conjugate Unlabeled
Format Purified
Formulation aqueous buffer, no sodium azide
Gene Alias Leu-4, T3
Host Species Mouse
Isotype IgG1
Quantity 500μg
Regulatory Status RUO
Species Reactivity Human
Storage Requirements Store at 2-8°C.
Primary or Secondary Primary
Monoclonal or Polyclonal Monoclonal

The SK7 monoclonal antibody reacts with human CD3e, a 20kDa subunit of the TCR complex. Along with the other CD3 subunits γ and δ, the ε chain is required for proper assembly, trafficking and surface expression of the TCR complex. CD3 is expressed by thymocytes in a developmentally regulated manner and by all mature T cells. The SK7 and UCHT1 monoclonal antibodies cross-block binding, suggesting recognition of overlapping epitopes.

The antibody SK7 recognizes chimpanzee CD3.