CD3 Mouse anti-Human, Clone: HIT3a, Functional Grade, eBioscience™

Mouse Monoclonal Antibody

Overview
Brand: Affymetrix eBioscience

Manufacturer Part Number: 16-0039-81

UNSPSC: 12352200

Code: Z2

Additional Details:
Additional Details: Weight: 0.01000kg



Disclaimers: For Research Use Only.

Product Code. 15208357

Quantity Price
1 £ 66.65 / 50µg
Estimated Shipment date
from Supplier 03-04-2017
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Description and Specification

Specification

Applications Flow Cytometry
Applications Functional Assay
Isotype IgG2a
Monoclonal or Polyclonal Monoclonal
Storage Requirements Store at 2-8°C.
Quantity 50μg
Antigen CD3
Species Reactivity Human
Primary or Secondary Primary
Format Purified
Clone HIT3a
Formulation aqueous buffer, no sodium azide
Regulatory Status RUO
Gene Alias Leu-4, T3
Host Species Mouse
Conjugate Unlabeled

The HIT3a monoclonal antibody reacts with human CD3e, a 20kDa subunit of the TCR complex. Along with the other CD3 subunits gamma and delta, the epsilon chain is required for proper assembly, trafficking and surface expression of the TCR complex. CD3 is expressed by thymocytes in a developmentally regulated manner and by all mature T cells. Crosslinking of TCR with HIT3a initiates an intracellular biochemical pathway resulting in cellular activation and proliferation.