CD3 Mouse anti-Human, Biotin, Clone: OKT3, eBioscience™

Mouse Monoclonal Antibody

Overview
Brand: Affymetrix eBioscience

Manufacturer Part Number: 13-0037-80

UNSPSC: 12352200

Code: Z2

Additional Details:
Additional Details: Weight: 0.25000kg



Disclaimers: For Research Use Only.

Product Code. 15209409

Quantity Price
1 £ 48.31 / 25µg
Estimated Shipment date
from Supplier 04-05-2017
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Description and Specification

Specification

Formulation aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer
Conjugate Biotin
Quantity 25μg
Primary or Secondary Primary
Format Conjugated
Monoclonal or Polyclonal Monoclonal
Gene Alias Leu-4, T3
Species Reactivity Human
Applications Flow Cytometry
Storage Requirements Store at 2-8°C. Do not freeze.
Regulatory Status RUO
Clone OKT3
Concentration 0.5mg/mL
Isotype IgG2a
Antigen CD3
Host Species Mouse

The OKT3 monoclonal antibody reacts with an epitope on the epsilon-subunit within the human CD3 complex. The OKT3 antibody has been reported to have potent immunosuppressive properties in vivo and has been proven effective in the treatment of renal, heart and liver allograft rejection. The CD3 subunits, gamma, delta, and epsilon chains, are required for proper assembly, trafficking and surface expression of the TCR complex. CD3 is expressed by thymocytes in a developmentally regulated manner and by all mature T cells. Crosslinking of TCR initiates an intracellular biochemical pathway resulting in cellular activation and proliferation.