CD3 Mouse anti-Human, APC-eFluor 780, Clone: UCHT1, eBioscience™

Mouse Monoclonal Antibody

Overview
Brand: Affymetrix eBioscience

Manufacturer Part Number: 47-0038-41

Code: NEW

Additional Details:
Additional Details: Weight: 0.23750kg



Disclaimers: For Research Use Only.

Product Code. 15559496

Quantity Price
1 £ 80.62 / 25 tests
Estimated Shipment date
from Supplier 02-05-2017
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Description and Specification

Specification

Concentration 5μL (0.5μg)/test
Gene Alias Leu-4, T3
Storage Requirements Store at 2-8°C. Do not freeze. Light-sensitive material. This tandem dye is sensitive to photo-induced oxidation. Protect this vial from light during storage
Formulation aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer
Conjugate APC-eFluor 780
Primary or Secondary Primary
Antigen CD3
Monoclonal or Polyclonal Monoclonal
Isotype IgG1
Host Species Mouse
Regulatory Status RUO
Clone UCHT1
Format Conjugated
Applications Flow Cytometry
Species Reactivity Human
Quantity 25 tests

The UCHT1 monoclonal antibody reacts with human CD3e, a 20kDa subunit of the TCR complex. Along with the other CD3 subunits gamma and delta, the epsilon chain is required for proper assembly, trafficking and surface expression of the TCR complex. CD3 is expressed by thymocytes in a developmentally regulated manner and by all mature T cells. Crosslinking of TCR via immobilized UCHT1 initiates an intracellular biochemical pathway resulting in cellular activation and proliferation.