CD3 Mouse anti-Human, APC-eFluor 780, Clone: OKT3, eBioscience™

Mouse Monoclonal Antibody

Overview
Brand: Affymetrix eBioscience

Manufacturer Part Number: 47-0037-42

Code: NEW

Additional Details:
Additional Details: Weight: 0.23750kg



Disclaimers: For Research Use Only.

Product Code. 15549496

Quantity Price
1 £ 205.24 / 100 tests
EU Stock 9
Add to basket


Description and Specification

Specification

Conjugate APC-eFluor 780
Quantity 100 tests
Applications Flow Cytometry
Isotype IgG2a
Regulatory Status RUO
Clone OKT3
Antigen CD3
Host Species Mouse
Monoclonal or Polyclonal Monoclonal
Species Reactivity Human
Storage Requirements Store at 2-8°C. Do not freeze. Light-sensitive material. This tandem dye is sensitive to photo-induced oxidation. Protect this vial from light during storage
Format Conjugated
Gene Alias Leu-4, T3
Primary or Secondary Primary
Concentration 5μL (0.125μg)/test
Formulation aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer

The OKT3 monoclonal antibody reacts with an epitope on the epsilon-subunit within the human CD3 complex. The OKT3 antibody has been reported to have potent immunosuppressive properties in vivo and has been proven effective in the treatment of renal, heart and liver allograft rejection. The CD3 subunits, gamma, delta, and epsilon chains, are required for proper assembly, trafficking and surface expression of the TCR complex. CD3 is expressed by thymocytes in a developmentally regulated manner and by all mature T cells. Crosslinking of TCR initiates an intracellular biochemical pathway resulting in cellular activation and proliferation.