CD3 Mouse anti-Human, APC, Clone: OKT3, eBioscience™

Mouse Monoclonal Antibody

Overview
Brand: Affymetrix eBioscience

Manufacturer Part Number: 17-0037-42

Code: NEW

Additional Details:
Additional Details: Weight: 0.23750kg



Disclaimers: For Research Use Only.

Product Code. 15537856

Quantity Price
1 £ 158.36 / 100 tests
EU Stock 7
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Description and Specification

Specification

Primary or Secondary Primary
Regulatory Status RUO
Format Conjugated
Gene Alias Leu-4, T3
Host Species Mouse
Monoclonal or Polyclonal Monoclonal
Formulation aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer
Quantity 100 tests
Conjugate APC
Isotype IgG2a
Antigen CD3
Storage Requirements Store at 2-8°C. Do not freeze. Light-sensitive material.
Clone OKT3
Species Reactivity Human
Concentration 5μL (0.06μg)/test
Applications Flow Cytometry

The OKT3 monoclonal antibody reacts with an epitope on the epsilon-subunit within the human CD3 complex. The OKT3 antibody has been reported to have potent immunosuppressive properties in vivo and has been proven effective in the treatment of renal, heart and liver allograft rejection. The CD3 subunits, gamma, delta, and epsilon chains, are required for proper assembly, trafficking and surface expression of the TCR complex. CD3 is expressed by thymocytes in a developmentally regulated manner and by all mature T cells. Crosslinking of TCR initiates an intracellular biochemical pathway resulting in cellular activation and proliferation.