CD299 (DC-SIGN/L) Mouse anti-Human, APC, Clone: 16E7, eBioscience™

Mouse Monoclonal Antibody

Overview
Brand: Affymetrix eBioscience

Manufacturer Part Number: 17-2999-42

Code: NEW

Additional Details:
Additional Details: Weight: 0.23750kg



Disclaimers: For Research Use Only.

Product Code. 15528076

Quantity Price
1 £ 182.82 / 100 tests
EU Stock 1
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Description and Specification

Specification

Antigen CD299 (DC-SIGN/L)
Applications Flow Cytometry
Clone 1.60E+08
Concentration 5μL (0.125μg)/test
Conjugate Allophycocyanin
Format Conjugated
Formulation aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer
Gene Alias Clec4M
Host Species Murine
Isotype IgG2a
Quantity 100 Tests
Regulatory Status RUO
Storage Requirements Store at 2-8°C. Do not freeze. Light-sensitive material.
Primary or Secondary Primary
Monoclonal or Polyclonal Monoclonal
Target Species Human

The 16E7 monoclonal antibody recognizes human CD299, which is also known as DC-SIGNR or L-SIGN. A homolog of DC-SIGN, CD299 is an oligomeric type II transmembrane protein expressed on dendritic cells, macrophages in the lung, and endothelial cells in the liver. This C-type lectin binds ICAM-3 to mediate the interaction between dendritic cells and T cells. CD299 also binds the gp120 protein of HIV and the E2 envelope protein of HCV, thereby playing a role in viral infection.