CD299 (DC-SIGN/L), APC, clone: 16E8, eBioscience™
Mouse Monoclonal Antibody
Brand: Affymetrix eBioscience 17-2999-42
Code : NEW
Additional Details : Weight : 0.23750kg
DescriptionDescription: The 16E7 monoclonal antibody recognizes human CD299, which is also known as DC-SIGNR or L-SIGN. A homolog of DC-SIGN, CD299 is an oligomeric type II transmembrane protein expressed on dendritic cells, macrophages in the lung, and endothelial cells in the liver. This C-type lectin binds ICAM-3 to mediate the interaction between dendritic cells and T cells. CD299 also binds the gp120 protein of HIV and the E2 envelope protein of HCV, thereby playing a role in viral infection.Applications Reported: This 16E7 antibody has been reported for use in flow cytometric analysis.Applications Tested: This 16E7 antibody has been pre-titrated and tested by flow cytometric analysis of normal human monocyte-derived dendritic cells. This can be used at 5 μL (0.125 μg) per test. A test is defined as the amount (μg) of antibody that will stain a cell sample in a final volume of 100 μL. Cell number should be determined empirically but can range from 10^5 to 10^8 cells/test.Excitation: 633-647 nm; Emission: 660 nm; Laser: Red Laser.Filtration: 0.2μm post-manufacturing filtered.
|PBS with 0.1% gelatin, 0.2% BSA and 0.09% sodium azide; pH 7.2|
|C-type lectin domain family 4 member M, CD209L, CD299, DC-SIGN2, DC-SIGNR, DCSIGNR, HP10347, L-SIGN, LSIGN, MGC129964, MGC47866|
|Store at 2-8°C. Do not freeze. Light-sensitive material.|
For Research Use Only.