CD294 (CRTH2), Biotin, clone: BM16, eBioscience™
Rat Monoclonal Antibody
Brand: Affymetrix eBioscience 13-2949-80
Code : NEW
Additional Details : Weight : 0.09500kg
DescriptionDescription: This BM16 monoclonal antibody reacts with human CD294, which is also known as G protein-coupled receptor-44 (GPR-44) or chemoattractant receptor expressed on Th2 cells (CRTH2). CD294 is expressed on Th2 cells, some CD8+ cells, eosinophils, and basophils. Moreover, CD294 binds prostaglandin D2, which promotes leukocyte chemotaxis during allergic responses. CD294 has been reported to mediate prostaglandin D2-mediated suppression of apoptosis of Th2 cells by activating the PI3K pathway.Applications Reported: This BM16 antibody has been reported for use in flow cytometric analysis.Applications Tested: This BM16 antibody has been tested by flow cytometric analysis of normal human peripheral blood cells. This can be used at less than or equal to 1 μg per test. A test is defined as the amount (μg) of antibody that will stain a cell sample in a final volume of 100 μL. Cell number should be determined empirically but can range from 10^5 to 10^8 cells/test. It is recommended that the antibody be carefully titrated for optimal performance in the assay of interest.Filtration: 0.2μm post-manufacturing filtered.
|PBS with 0.1% gelatin and 0.09% sodium azide; pH 7.2|
|Crth2, Grp45, MGC130436|
|Store at 2-8°C. Do not freeze.|
For Research Use Only.