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CD294 (CRTH2) Rat anti-Human, Biotin, Clone: BM16, eBioscience™

Rat Monoclonal Antibody

Brand:  Affymetrix eBioscience 13-2949-82

Code : NEW

Additional Details : Weight : 0.09500kg

Product Code. 15597326

  • £78.25 / 100µg

Estimated Shipment date
from Supplier 02-04-2020

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Description

Description

The prostaglandin D2 receptor 2 (PTGDR2), also known as CRTH2, is expressed on Th2 cells and eosinophils and mediates chemotaxis of these cells to PGD2 and is thus thought to be a key receptor mediating eosinophil and Th2 recruitment during allergic responses. However, PTGDR2-null mice showed enhanced eosinophil recruitment into the lung consistent with observations that the PTGDR2-null mice produced significantly higher amounts of interleukin-5 (IL-5) and IL-3. This suggests that PTGDR2 plays a nonredundant role in restricting eosinophilia and allergic response in vivo.
Specifications

Specifications

CD294 (CRTH2)
Monoclonal
0.5 mg/mL
PBS with 0.1% gelatin and 0.09% sodium azide; pH 7.2
Q9Y5Y4
Crth2, Grp45, MGC130436
Rat
Affinity chromatography
RUO
Antibody
Monoclonal
Human
Flow Cytometry
BM16
Biotin
PTGDR2
Liquid
PTGDR2
IgG2a
100 μg
4° C, store in dark, DO NOT FREEZE!
Primary
11251
Videos
Documents

For Research Use Only.