CD294 (CRTH2) Rat anti-Human, Biotin, Clone: BM16, eBioscience™
Rat Monoclonal Antibody
Brand: Affymetrix eBioscience 13-2949-82
Code : NEW
Additional Details : Weight : 0.09500kg
DescriptionThe prostaglandin D2 receptor 2 (PTGDR2), also known as CRTH2, is expressed on Th2 cells and eosinophils and mediates chemotaxis of these cells to PGD2 and is thus thought to be a key receptor mediating eosinophil and Th2 recruitment during allergic responses. However, PTGDR2-null mice showed enhanced eosinophil recruitment into the lung consistent with observations that the PTGDR2-null mice produced significantly higher amounts of interleukin-5 (IL-5) and IL-3. This suggests that PTGDR2 plays a nonredundant role in restricting eosinophilia and allergic response in vivo.
|PBS with 0.1% gelatin and 0.09% sodium azide; pH 7.2|
|Crth2, Grp45, MGC130436|
|4° C, store in dark, DO NOT FREEZE!|
For Research Use Only.