CD294 (CRTH2) Rat anti-Human, eFluor 660, Clone: BM16, eBioscience™

Rat Monoclonal Antibody

Overview
Brand: Affymetrix eBioscience

Manufacturer Part Number: 50-2949-41

Code: NEW

Additional Details:
Additional Details: Weight: 0.23750kg



Disclaimers: For Research Use Only.

Product Code. 15599916

Quantity Price
1 £ 60.53 / 25 tests
Estimated Shipment date
from Supplier 05-05-2017
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Description and Specification

Specification

Clone BM16
Species Reactivity Human
Formulation aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer
Antigen CD294 (CRTH2)
Host Species Rat
Storage Requirements Store at 2-8°C. Do not freeze. Light-sensitive material.
Monoclonal or Polyclonal Monoclonal
Regulatory Status RUO
Conjugate eFluor 660
Primary or Secondary Primary
Quantity 25 tests
Applications Flow Cytometry
Format Conjugated
Concentration 5μL (0.25μg)/test
Isotype IgG2a

This BM16 monoclonal antibody reacts with human CD294, which is also known as G protein-coupled receptor-44 (GPR-44) or chemoattractant receptor expressed on Th2 cells (CRTH2). CD294 is expressed on Th2 cells, some CD8+ cells, eosinophils, and basophils. Moreover, CD294 binds prostaglandin D2, which promotes leukocyte chemotaxis during allergic responses. CD294 has been reported to mediate prostaglandin D2-mediated suppression of apoptosis of Th2 cells by activating the PI3K pathway.