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CD29 (Integrin beta 1) Monoclonal Antibody (eBioHMb1-1 (HMb1-1)), PE-Cyanine7, eBioscience™, Invitrogen™
Armenian Hamster Monoclonal Antibody
Brand: Affymetrix eBioscience 25-0291-82
166.00 GBP valid until 2024-03-29
Use promo code "21615" to get your promotional price.
Code : Z2
Additional Details : Weight : 0.25000kg
Description
CD29 (beta1 integrin subunit, GPIIa) forms non-covalently linked heterodimers with at least 6 different alpha chains (alpha1-alpha6, CD49a-f) determining the binding properties of beta1 (VLA) integrins. These integrins mediate cell adhesion to collagen, fibronectin, laminin and other extracellular matrix (ECM) components. This interaction hinders cell death, whereas disruption of anchorage to ECM leads to apoptosis. Decreased expression of most beta1 integrins correlates with acquiring multidrug resistance of tumour cells during selection in presence of antitumour drug. In platelets, translocation of intracellular pool of beta1 integrins to the plasma membrane following thrombin stimulation. These integrins are also up-regulated in leukocytes during emigration and extravascular migration and appear to be critically involved in regulating the immune cell trafficking from blood to tissue, as well as in regulating tissue damage and disease symptoms related to inflammatory bowel disease. Through a beta1 integrin-dependent mechanism, fibronectin and type I collagen enhance cytokine secretion of human airway smooth muscle in response to IL-1beta.
CD29 (Integrin beta 1) Monoclonal antibody specifically detects CD29 (Integrin beta 1) in Mouse, Rat samples. It is validated for Flow Cytometry.Specifications
CD29 (Integrin beta 1) | |
Monoclonal | |
0.2 mg/mL | |
PBS with 0.09% sodium azide; pH 7.2 | |
P09055, P49134 | |
ITGB1 | |
Affinity chromatography | |
RUO | |
16412, 24511 | |
4° C, store in dark, DO NOT FREEZE! | |
Liquid |
Flow Cytometry | |
eBioHMb1-1 (HMb1-1) | |
PE-Cyanine7 | |
ITGB1 | |
4633401G24Rik; AA409975; AA960159; Beta OL; beta oligodendroglia; CD29; CSAT antigen; ENSMUSG00000051907; Fibronectin receptor subunit beta; FNRB; Glycoprotein IIa; Gm9863; gpIIa; integrin beta 1; integrin beta 1 (fibronectin receptor beta); integrin beta 1A precursor; Integrin beta1; integrin beta-1; integrin beta-1 subunit; integrin beta1D; integrin precursor; integrin subunit beta 1; integrin VLA-4 beta subunit; integrin VLA-4 subunit beta; integrin, beta 1; integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12); ITBG1D; ITGB1; JG22 antigen; MDF2; MSK12; RGD-receptor; very late activation protein, beta polypeptide; VLA-4 subunit beta; VLAB; VLA-BETA | |
Armenian Hamster | |
100 μg | |
Primary | |
Mouse, Rat | |
Antibody | |
IgG |
For Research Use Only.