CD282 (TLR2) Rat anti-Mouse, Clone: 6C2, Functional Grade, eBioscience™

Rat Monoclonal Antibody, Functional Grade

Overview
Brand: Affymetrix eBioscience

Manufacturer Part Number: 16-9021-83

UNSPSC: 12352200

Code: Z2

Additional Details:
Additional Details: Weight: 0.01000kg



Disclaimers: For Research Use Only.

Product Code. 15268817

Quantity Price
1 £ 231.74 / 200µg
Estimated Shipment date
from Supplier 04-05-2017
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Description and Specification

Specification

Species Reactivity Mouse
Monoclonal or Polyclonal Monoclonal
Gene Alias TLR-2, toll-like receptor 2
Antigen CD282 (TLR2)
Isotype IgG2b
Concentration 1mg/mL
Primary or Secondary Primary
Clone 6C2
Conjugate Unlabeled
Regulatory Status RUO
Storage Requirements Store at 2-8°C.
Formulation aqueous buffer, no sodium azide
Quantity 200μg
Applications Flow Cytometry
Format Purified
Host Species Rat

The 6C2 monoclonal antibody reacts with mouse Toll-like receptor 2 (TLR2). Mouse TLR2 is expressed by the myeloid lineage, including macrophage and dendritic cells in splenocytes and the RAW264.7 cell line. To date, at least twelve members of the Toll family have been identified in human and mouse. This family of type I transmembrane proteins is characterized by an extracellular domain with leucine-rich repeats and a cytoplasmic domain with homology to the type I IL-1 receptor. Two of these receptors, TLR2 and TLR4, are pattern recognition receptors and signaling molecules in response to bacterial lipoproteins and have been implicated in innate immunity and inflammation. TLR2 is expressed on the surface of cells and is responsible for distinguishing different pathogens.