CD282 (TLR2) Rat anti-Mouse, Clone: 6C2, Functional Grade, eBioscience™

Rat Monoclonal Antibody, Functional Grade

Overview
Brand: Affymetrix eBioscience

Manufacturer Part Number: 16-9021-81

UNSPSC: 12352200

Code: Z2

Additional Details:
Additional Details: Weight: 0.01000kg



Disclaimers: For Research Use Only.

Product Code. 15258817

Quantity Price
1 £ 91.11 / 50µg
Estimated Shipment date
from Supplier 03-04-2017
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Description and Specification

Specification

Gene Alias TLR-2, toll-like receptor 2
Concentration 1mg/mL
Conjugate Unlabeled
Formulation aqueous buffer, no sodium azide
Monoclonal or Polyclonal Monoclonal
Isotype IgG2b
Clone 6C2
Format Purified
Regulatory Status RUO
Species Reactivity Mouse
Applications Flow Cytometry
Primary or Secondary Primary
Antigen CD282 (TLR2)
Storage Requirements Store at 2-8°C.
Host Species Rat
Quantity 50μg

The 6C2 monoclonal antibody reacts with mouse Toll-like receptor 2 (TLR2). Mouse TLR2 is expressed by the myeloid lineage, including macrophage and dendritic cells in splenocytes and the RAW264.7 cell line. To date, at least twelve members of the Toll family have been identified in human and mouse. This family of type I transmembrane proteins is characterized by an extracellular domain with leucine-rich repeats and a cytoplasmic domain with homology to the type I IL-1 receptor. Two of these receptors, TLR2 and TLR4, are pattern recognition receptors and signaling molecules in response to bacterial lipoproteins and have been implicated in innate immunity and inflammation. TLR2 is expressed on the surface of cells and is responsible for distinguishing different pathogens.