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CD282 (TLR2) Rat anti-Mouse, Clone: 6C2, eBioscience™

Rat Monoclonal Antibody

Brand:  Affymetrix eBioscience 14-9021-82

UNSPSC : 12352200

Code : Z2

Additional Details : Weight : 0.01000kg

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Product Code. 15278127

  • £152.25 / 100µg


Estimated Shipment
07-07-2017
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Disclaimers:

For Research Use Only.


Specifications

Description

The 6C2 monoclonal antibody reacts with mouse Toll-like receptor 2 (TLR2). Mouse TLR2 is expressed by the myeloid lineage, including macrophage and dendritic cells in splenocytes and the RAW264.7 cell line. To date, at least twelve members of the Toll family have been identified in human and mouse. This family of type I transmembrane proteins is characterized by an extracellular domain with leucine-rich repeats and a cytoplasmic domain with homology to the type I IL-1 receptor. Two of these receptors, TLR2 and TLR4, are pattern recognition receptors and signaling molecules in response to bacterial lipoproteins and have been implicated in innate immunity and inflammation. TLR2 is expressed on the surface of cells and is responsible for distinguishing different pathogens.
Description & Specifications

Specifications

CD282 (TLR2)
6C2
Unlabeled
aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer
Rat
100μg
Store at 2-8°C.
Monoclonal
Immunoprecipitation
0.5mg/mL
Purified
toll-like receptor 2
IgG2b
RUO
Primary
Murine