CD282 (TLR2) Mouse anti-Mouse, PE, Clone: mT2.7, eBioscience™

Mouse Monoclonal Antibody

Overview
Brand: Affymetrix eBioscience

Manufacturer Part Number: 12-9022-80

UNSPSC: 12352200

Code: Z2

Additional Details:
Additional Details: Weight: 0.25000kg



Disclaimers: For Research Use Only.

Product Code. 15289339

Quantity Price
1 £ 72.77 / 25µg
Estimated Shipment date
from Supplier 05-05-2017
Add to basket


Description and Specification

Specification

Isotype IgG2a
Species Reactivity Mouse
Clone mT2.7
Antigen CD282 (TLR2)
Monoclonal or Polyclonal Monoclonal
Primary or Secondary Primary
Concentration 0.2mg/mL
Regulatory Status RUO
Gene Alias toll-like receptor 2
Host Species Mouse
Applications Flow Cytometry
Format Conjugated
Quantity 25μg
Storage Requirements Store at 2-8°C. Do not freeze. Light-sensitive material.
Conjugate PE
Formulation aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer

The mT2.7 monoclonal antibody reacts with mouse Toll-like receptor 2 (TLR2). Mouse TLR2 is expressed by the myeloid lineage, including macrophage and dendritic cells in splenocytes and the RAW264.7 cell line. To date, at least twelve members of the Toll family have been identified in human and mouse. This family of type I transmembrane protein is characterized by an extracellular domain with leucine-rich repeats and a cytoplasmic domain with homology to the type I IL-1 receptor. Two of these receptors, TLR2 and TLR4, are pattern recognition receptors and signaling molecules in response to bacterial lipoproteins and have been implicated in innate immunity and inflammation. TLR2 is expressed on the surface of cells and is responsible for distinguishing different pathogens.