CD282 (TLR2) Mouse anti-Mouse, FITC, Clone: mT2.7, eBioscience™

Mouse Monoclonal Antibody

Overview
Brand: Affymetrix eBioscience

Manufacturer Part Number: 11-9022-82

UNSPSC: 12352200

Code: Z2

Additional Details:
Additional Details: Weight: 0.25000kg



Disclaimers: For Research Use Only.

Product Code. 15258379

Quantity Price
1 £ 170.59 / 100µg
Estimated Shipment date
from Supplier 04-05-2017
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Description and Specification

Specification

Antigen CD282 (TLR2)
Format Conjugated
Regulatory Status RUO
Gene Alias toll-like receptor 2
Species Reactivity Mouse
Conjugate FITC
Monoclonal or Polyclonal Monoclonal
Concentration 0.5mg/mL
Applications Flow Cytometry
Primary or Secondary Primary
Isotype IgG2a
Clone mT2.7
Storage Requirements Store at 2-8°C. Do not freeze. Light-sensitive material.
Quantity 100μg
Host Species Mouse
Formulation aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer

The mT2.7 monoclonal antibody reacts with mouse Toll-like receptor 2 (TLR2). Mouse TLR2 is expressed by the myeloid lineage, including macrophage and dendritic cells in splenocytes and the RAW264.7 cell line. To date, at least twelve members of the Toll family have been identified in human and mouse. This family of type I transmembrane protein is characterized by an extracellular domain with leucine-rich repeats and a cytoplasmic domain with homology to the type I IL-1 receptor. Two of these receptors, TLR2 and TLR4, are pattern recognition receptors and signaling molecules in response to bacterial lipoproteins and have been implicated in innate immunity and inflammation. TLR2 is expressed on the surface of cells and is responsible for distinguishing different pathogens.