CD282 (TLR2) Mouse anti-Human, Clone: TL2.1, Functional Grade, eBioscience™

Mouse Monoclonal Antibody, Functional Grade

Brand: Affymetrix eBioscience

Manufacturer Part Number: 16-9922-82

UNSPSC: 12352200

Code: Z2

Additional Details:
Additional Details: Weight: 0.01000kg

Disclaimers: For Research Use Only.

Product Code. 15268837

Quantity Price
1 £ 164.47 / 100µg
EU Stock 3
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Description and Specification


Regulatory Status RUO
Isotype IgG2a
Format Purified
Quantity 100μg
Conjugate Unlabeled
Applications Flow Cytometry
Applications Functional Assay
Host Species Mouse
Primary or Secondary Primary
Gene Alias toll-like receptor 2
Species Reactivity Human
Storage Requirements Store at 2-8°C.
Formulation aqueous buffer, no sodium azide
Monoclonal or Polyclonal Monoclonal
Clone TL2.1
Concentration 1mg/mL
Antigen CD282 (TLR2)

The TL2.1 monoclonal antibody reacts with human Toll-like receptor 2 (TLR2). To date, at least ten members of the Toll family have been identified in human. This family of type I transmembrane proteins is characterized by an extracellular domain with leucine-rich repeats and a cytoplasmic domain with homology to the type I IL-1 receptor. Two of these receptors, TLR2 and TLR4, are pattern recognition receptors and signaling molecules in response to bacterial lipoproteins and have been implicated in innate immunity and inflammation. TLR2 is expressed by peripheral blood monocytes and is responsible for distinguishing different pathogens. TL2.1, a blocking antibody, has been used to study the role of TLR-2 as a pattern recognition receptor in microbial lipoprotein/lipopeptide induced cytokine production from human peripheral blood mononuclear cells. TL2.1 has been reported to immunoprecipitate human TLR2 (~90kDa) from PBMC and HMEC.