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CD282 (TLR2) Mouse anti-Human, Alexa Fluor 488, Clone: TL2.1, eBioscience™

Mouse Monoclonal Antibody

Brand:  Affymetrix eBioscience 53-9922-42

Code : NEW

Additional Details : Weight : 0.23750kg

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Product Code. 15570317

  • £176.70 / 100 tests


Estimated Shipment date
from Supplier 02-08-2017
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Disclaimers:

For Research Use Only.


Specifications

Description

The TL2.1 monoclonal antibody reacts with human Toll-like receptor 2 (TLR2). To date, at least ten members of the Toll family have been identified in human. This family of type I transmembrane proteins is characterized by an extracellular domain with leucine-rich repeats and a cytoplasmic domain with homology to the type I IL-1 receptor. Two of these receptors, TLR2 and TLR4, are pattern recognition receptors and signaling molecules in response to bacterial lipoproteins and have been implicated in innate immunity and inflammation. TLR2 is expressed by peripheral blood monocytes and is responsible for distinguishing different pathogens. TL2.1, a blocking antibody, has been used to study the role of TLR-2 as a pattern recognition receptor in microbial lipoprotein/lipopeptide induced cytokine production from human peripheral blood mononuclear cells. TL2.1 has been reported to immunoprecipitate human TLR2 (∽90 kDa) from PBMC and HMEC.
Description & Specifications

Specifications

CD282 (TLR2)
TL2.1
Alexa Fluor 488
aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer
Murine
100 Tests
Store at 2-8°C. Do not freeze. Light-sensitive material.
Monoclonal
Flow Cytometry
5μL (1.0μg)/test
Conjugated
toll-like receptor 2
IgG2a
RUO
Primary
Human