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CD281 (TLR1) Rat anti-Mouse, eFluor 660, Clone: eBioTR23 (TR23), eBioscience™

Rat Monoclonal Antibody

Brand:  Affymetrix eBioscience 50-9011-80

Code : NEW

Additional Details : Weight : 0.09500kg

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Product Code. 15500067

This item has been discontinued and is no longer available. View the product for possible alternatives or contact our Product Support team on 01509 555888 for assistance

Disclaimers:

For Research Use Only.


Description

Description

The eBioTR23 monoclonal antibody reacts with mouse Toll-like receptor 1 (TLR1, CD281). TLR1 is an approximately 98kDa protein belonging to the Toll-like receptor family, and is closely-related to mouse TLR6 in both structure and function. Through the formation of a complex with TLR2, TLR1 is able to bind bacterially-derived triacyl lipopeptides, as well as soluble factors released from Neisseria meningitidis. TLR1 is expressed by macrophages and macrophages in TLR1-deficient mice display impaired production of inflammatory cytokines upon stimulation with triacyl lipopeptides and lipoproteins from mycobacteria.
Specifications

Specifications

CD281 (TLR1)
eBioTR23 (TR23)
eFluor 660
Conjugated
Rat
25μg
Store at 2-8°C. Do not freeze. Light-sensitive material.
Monoclonal
Flow Cytometry
0.2mg/mL
aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer
Toll-like Receptor 1
IgG2a
RUO
Primary
Murine