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CD279 (PD-1) Rat anti-Mouse, PerCP-eFluor 710, Clone: RMP1-30, eBioscience™

Rat Monoclonal Antibody

Brand:  Affymetrix eBioscience 46-9981-80

UNSPSC : 12352200

Code : Z2

Additional Details : Weight : 0.25000kg

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Product Code. 15321410

  • £75.30 / 25µg


Estimated Shipment
03-08-2017
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Disclaimers:

For Research Use Only.


Specifications

Description

The RMP1-30 antibody reacts with mouse PD-1 (programmed death-1), a 55kDa member of the Ig superfamily. PD-1 contains the immunoreceptor tyrosine-based inhibitory motif (ITIM) and plays a key role in peripheral tolerance and autoimmune disease in mice. PD-1 is expressed mainly on activated T and B lymphocytes. Two novel B7 Family members have been identified as PD-1 ligands, PD-L1 (B7-H1) and PD-L2 (B7-DC). Evidence reported to date suggests overlapping functions for these ligands and their constitutive expression on some normal tissues and upregulation on activated antigen-presenting cells. RMP1–30 does not block the binding of either B7-H1-Ig or B7-DC-Ig to PD-1 transfectants.
Description & Specifications

Specifications

CD279 (PD-1)
RMP1-30
PerCP-eFluor 710
aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer
Rat
25μg
Store at 2-8°C. Do not freeze. Light-sensitive material.
Monoclonal
Flow Cytometry
0.2mg/mL
Conjugated
Pdcd1, Programmed cell death protein 1
IgG2b
RUO
Primary
Murine