CD279 (PD-1), clone: RMP1-30, eBioscience™
Rat Monoclonal Antibody
Brand: Affymetrix eBioscience 14-9981-85
Code : Z2
Additional Details : Weight : 0.01000kg
DescriptionThe RMP1-30 antibody reacts with mouse PD-1 (programmed death-1), a 55kDa member of the Ig superfamily. PD-1 contains the immunoreceptor tyrosine-based inhibitory motif (ITIM) and plays a key role in peripheral tolerance and autoimmune disease in mice. PD-1 is expressed mainly on activated T and B lymphocytes. Two novel B7 Family members have been identified as PD-1 ligands, PD-L1 (B7-H1) and PD-L2 (B7-DC). Evidence reported to date suggests overlapping functions for these ligands and their constitutive expression on some normal tissues and upregulation on activated antigen-presenting cells. RMP1–30 does not block the binding of either B7-H1-Ig or B7-DC-Ig to PD-1 transfectants.
|Store at 2-8°C.|
|aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer|
|Pdcd1, Programmed cell death protein 1|
For Research Use Only.