missing translation for 'onlineSavingsMsg'
Learn More

CD279 (PD-1) Rat anti-Mouse, Biotin, Clone: RMP1-30, eBioscience™

Rat Monoclonal Antibody

Brand:  Affymetrix eBioscience 13-9981-82

UNSPSC : 12352200

Code : Z2

Additional Details : Weight : 0.25000kg

 View more versions of this product

Product Code. 15370140

  • £97.22 / 100µg


Estimated Shipment date
from Supplier 26-09-2017
Add to basket

Disclaimers:

For Research Use Only.


Description

Description

The RMP1-30 antibody reacts with mouse PD-1 (programmed death-1), a 55kDa member of the Ig superfamily. PD-1 contains the immunoreceptor tyrosine-based inhibitory motif (ITIM) and plays a key role in peripheral tolerance and autoimmune disease in mice. PD-1 is expressed mainly on activated T and B lymphocytes. Two novel B7 Family members have been identified as PD-1 ligands, PD-L1 (B7-H1) and PD-L2 (B7-DC). Evidence reported to date suggests overlapping functions for these ligands and their constitutive expression on some normal tissues and upregulation on activated antigen-presenting cells. RMP1–30 does not block the binding of either B7-H1-Ig or B7-DC-Ig to PD-1 transfectants.
Specifications

Specifications

CD279 (PD-1)
RMP1-30
Biotin
Conjugated
Rat
100μg
Store at 2-8°C. Do not freeze.
Monoclonal
Flow Cytometry
0.5mg/mL
aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer
Pdcd1, Programmed cell death protein 1
IgG2b
RUO
Primary
Murine