missing translation for 'onlineSavingsMsg'
Learn More

CD279 (PD-1) Mouse anti-Human, PerCP-eFluor 710, Clone: eBioJ105 (J105), eBioscience™

Mouse Monoclonal Antibody

Brand:  Affymetrix eBioscience 46-2799-42

Code : Z2

Additional Details : Weight : 0.01000kg

 View more versions of this product

Product Code. 15572696

  • £208.18 / 100 tests


Estimated Shipment
30-11-2017
Add to basket

Disclaimers:

For Research Use Only.


Description

Description

The J105 monoclonal antibody reacts with the human PD-1 (programmed death-1), a 55kDa member of the CD28 immunoglobulin superfamily. PD-1 contains the immunoreceptor tyrosine-based inhibitory motif (ITIM) and plays a key role in peripheral tolerance and autoimmune disease. PD-1 is expressed predominantly on activated T and B lymphocytes. Two novel members of the B7 family have been identified as the PD-1 ligands, PD-L1 (B7-H1) and PD-L2 (B7-DC). Evidence reported to date suggests overlapping functions for these two PD-1 ligands and their constitutive expression on some normal tissues and upregulation on activated antigen-presenting cells.
Costaining experiments suggest that eBioJ105 recognizes a different epitope than MIH4 (cat. 11-9969).
Specifications

Specifications

CD279 (PD-1)
eBioJ105 (J105)
PerCP-eFluor™ 710
Conjugated
Murine
100 Tests
Store at 2-8°C. Do not freeze. Light-sensitive material.
Monoclonal
Flow Cytometry
5μL (0.25μg)/test
aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer
PD1
IgG1
RUO
Primary
Human
Videos