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CD279 (PD-1) Mouse anti-Human, Rhesus Monkey, PerCP-eFluor™ 710, Clone: eBioJ105 (J105), eBioscience™

Mouse Monoclonal Antibody

Brand:  Affymetrix eBioscience 46-2799-42

Code : Z2

Additional Details : Weight : 0.01000kg

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Product Code. 15572696

  • £219.00 / 100 tests

In stock, ready to ship: 2

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Description

Description

Please make sure that your instrument is capable of detecting this fluorochrome. For a filter configuration, we recommend using the 685 LP dichroic mirror and 710/40 band pass filter, however the 695/40 band pass filter is an acceptable alternative. Our testing indicates that PerCP-eFluor® 710 conjugated antibodies are stable when stained samples are exposed to freshly prepared 2% formaldehyde overnight at 4°C, but please evaluate for alternative fixation protocols. Excitation: 488 nm; Emission: 710 nm; Laser: Blue Laser. Filtration: 0.2 μm post-manufacturing filtered. Cell-mediated immune responses are initiated by T lymphocytes that are themselves stimulated by cognate peptides bound to MHC molecules on antig en-presenting cells (APC). T-cell activation is generally self-limited as activated T cells express receptors such as PD-1 (also known as PDCD-1) that mediate inhibitory signals from the APC. PD-1 can bind two different but related ligands, PDL-1 and PDL-2. Upon binding to either of these ligands, signals generated by PD-1 inhibit the activation of the immune response in the absence of ""danger signals"" such as LPS or other molecules associated with bacteria or other pathogens. Evidence for this is seen in PD1-null mice who exhibit hyperactivated immune systems and autoimmune diseases. Despite its predicted molecular weight, PD-1 often migrates at higher molecular weight in SDS-PAGE.
Specifications

Specifications

CD279 (PD-1)
Monoclonal
5 μL/Test
PBS with 0.1% gelatin, 0.2% BSA and 0.09% sodium azide; pH 7.2
Q15116
PD1
Mouse
Affinity chromatography
RUO
Antibody
Monoclonal
Human, Rhesus Monkey
Flow Cytometry
eBioJ105 (J105)
PerCP-eFluor™ 710
PDCD1
Liquid
PDCD1
IgG1, kappa
100 Tests
4° C, store in dark, DO NOT FREEZE!
Primary
100135775, 5133
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