CD279 (PD-1) Mouse anti-Human, PE-eFluor 610, Clone: eBioJ105 (J105), eBioscience™

Mouse Monoclonal Antibody

Overview
Brand: Affymetrix eBioscience

Manufacturer Part Number: 61-2799-41

25TEST Anti-Human CD279 (PD-1) PE-eFluor 610

Code: NEW

Additional Details:
Additional Details: Weight: 0.23750kg



Disclaimers: For Research Use Only.

Product Code. 15580477

Quantity Price
1 £ 86.73 / 25 tests
Estimated Shipment date
from Supplier 27-02-2017
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Description and Specification

Specification

Storage Requirements Store at 2-8°C. Do not freeze. Light-sensitive material. This tandem dye is sensitive to photo-induced oxidation. Protect this vial from light during storage
Antigen CD279 (PD-1)
Format Conjugated
Formulation aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer
Host Species Mouse
Applications Flow Cytometry
Isotype IgG1
Quantity 25 tests
Regulatory Status RUO
Species Reactivity Human
Primary or Secondary Primary
Monoclonal or Polyclonal Monoclonal
Clone eBioJ105 (J105)
Concentration 5μL (0.5μg)/test
Conjugate PE-eFluor 610

The J105 monoclonal antibody reacts with the human PD-1 (programmed death-1), a 55kDa member of the CD28 immunoglobulin superfamily. PD-1 contains the immunoreceptor tyrosine-based inhibitory motif (ITIM) and plays a key role in peripheral tolerance and autoimmune disease. PD-1 is expressed predominantly on activated T and B lymphocytes. Two novel members of the B7 family have been identified as the PD-1 ligands, PD-L1 (B7-H1) and PD-L2 (B7-DC). Evidence reported to date suggests overlapping functions for these two PD-1 ligands and their constitutive expression on some normal tissues and upregulation on activated antigen-presenting cells.

Costaining experiments suggest that eBioJ105 recognizes a different epitope than MIH4 (cat. 11-9969).